OPTIMIZATION AND CHARACTERIZATION OF ION ACTIVATED OCULAR IN-SITU GEL FORMULATION FOR BACTERIAL CONJUNCTIVITIS
نویسندگان
چکیده
منابع مشابه
Norfloxacin loaded pH triggered nanoparticulate in situ gel for extraocular bacterial infections: Optimization, ocular irritancy and corneal toxicity
In order to achieve prolong corneal contact time of norfloxacin(NFX) for treatment of extra ocular diseases, a pH triggered nanoparticulate in situ gelling system was designed to explore dual advantage of nanoparticles and in situ gelling system, for its ocular delivery. NFX loaded nanocarriers were developed by ionotropic gelation technique using chitosan as a matrix forming polymer, cross-lin...
متن کاملNorfloxacin loaded pH triggered nanoparticulate in situ gel for extraocular bacterial infections: Optimization, ocular irritancy and corneal toxicity
In order to achieve prolong corneal contact time of norfloxacin(NFX) for treatment of extra ocular diseases, a pH triggered nanoparticulate in situ gelling system was designed to explore dual advantage of nanoparticles and in situ gelling system, for its ocular delivery. NFX loaded nanocarriers were developed by ionotropic gelation technique using chitosan as a matrix forming polymer, cross-lin...
متن کاملPreparation and characterization of bear bile-loaded pH sensitive in-situ gel eye drops for ocular drug delivery
Objective(s): In this study, a stable bear bile-loaded pH sensitive in-situ eye drop gel was prepared for sustain delivery and enhanced therapeutic application. Materials and Methods: Bear bile-loaded in-situ ocular gels with different Carbopol/Hydroxypropyl methylcellulose (HPMC) ratios were prepared and their stability was tested in P...
متن کاملnorfloxacin loaded ph triggered nanoparticulate in situ gel for extraocular bacterial infections: optimization, ocular irritancy and corneal toxicity
in order to achieve prolong corneal contact time of norfloxacin(nfx) for treatment of extra ocular diseases, a ph triggered nanoparticulate in situ gelling system was designed to explore dual advantage of nanoparticles and in situ gelling system, for its ocular delivery. nfx loaded nanocarriers were developed by ionotropic gelation technique using chitosan as a matrix forming polymer, cross-lin...
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Abstract Bacterial conjunctivitis characterized as pink eye referred as an inflammation of an eye caused by the enlargement of blood vessels present in conjunctiva, resulting in a red or bloodshot appearance of the eyes. Topical ocular delivery is found to be useful in treating conjunctivitis, but to maintain an effective drug concentration at a site of action in order to achieve desired pha...
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ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2020
ISSN: 0975-7058
DOI: 10.22159/ijap.2020v12i4.37925